ea0004p29 | Cytokines and growth factors | SFE2002
Patel N
, Lowy C
, Carr R
, Jupp R
, Wheeler M
Acute critical illness has an effect on normal physiology resulting in changes in the inter-relations of the endocrine system.Evidence suggests that these changes may be due to the pro-inflammatory cytokines (e.g. interleukin-6 (IL-6)), which are known to have a paradoxical effect on the hypothalamo-pituitary axis, stimulating the adrenal axis, whilst suppressing the remaining axes.Multiple myeloma (MM) patients have elevated IL-6 ...